Department of Experimental Clinical Oncology

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572.      Alsner, J., Guldberg, P., Yilmas, M., Hansen, L.L.. & Overgaard, J.: Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients. Clin. Cancer Research 6: 3923-3931, 2000.

573.      Andersen, L., Højris, I., Erlandsen, M. & Andersen, J.: Treatment of breast cancer related lymphedema with or without manual lymphatic drainage: a randomized study. Acta Oncologica 39: 399-406, 2000.

574.      Bentzen, L., Keiding, S., Horsman, M.R., Falborg, L., Hansen, S.B. & Overgaard, J.: Feasibility of detecting hypoxia in experimental mouse tumours with 18-F-fluorinated tracers and positron emission tomography: A study evaluating 18F-Fluoromisonidazole and 18F-Fluoro-2-deoxy-D-glucose. Acta Oncologica 39: 629-637, 2000.

575.      Bentzen, L., Maxwell, R.J., Horsman, M.R. & Daugaard, P.: Noninvasive tumour perfusion measurement by 2H magnetic resonance. NMR biomed. 13: 1-9, 2000.

576.      Bentzen, S.M., Skoczylas, J.Z. & Bernier, J.: Quantitative clinical radiobiology of early and late lung reactions. Int. J. Radiat. Biol. 76: 453-462, 2000.

577.      Borre, M., Nerstrøm, B. & Overgaard, J.: Association between immunohistochemical expression of vascular endothelial growth factor (VEGF), VEGF-expressing neuroendocrine-differentiated tumor cells, and outcome in prostate cancer patients subjected to watchful waiting. Clin. Cancer Res. 6: 1882-90, 2000.

578.      Borre, M., Stausbøl-Grøn, B. & Overgaard, J.: p53 accumulation associated with bcl-2, the proliferation marker MIB-1 and survival in prostate cancer patients subjected to watchful waiting. J. Urol. 164: 716-721, 2000. 

579.      Dikomey, E., Brammer, I., Johansen, J., Bentzen, S.M. & Overgaard, J.: Relationship between DNA double-strand breaks, cell killing, and fibrosis studied in confluent skin fibroblasts derived from breast cancer patients. Int. J. Radiat. Oncol. Biol. Phys. 46: 481-490, 2000.

580.      Grau, C., Vendelbo Johansen, L., Jakobsen, J., Geertsen, P., Andersen, E., Bjerregaard Jensen, B.: Cervical lymph node metastases from unknown primary tumors. Results from a national survey by the Danish Society for Head and Neck Oncology. Radiotherapy and Oncology 55: 121-129, 2000.

581.      Hald, J.: Tobaksrygning og strålebehandling. Diploma study (Master of Medical Science) Faculty of Health Sciences, University of Aarhus, 2000.

582.      Herskind, C. & Rodemann, H.P.: Spontaneous and radiation-induced differentiation of fibroblasts. Experimental Gerontology 35: 747-755, 2000.

583.      Herskind, C., Johansen, J., Bentzen, S.M., Overgaard, M., Overgaard, J., Bamberg, M. & Rodemann, H.P.: Fibroblast differentiation in subcutaneous fibrosis after postmastectomy radiotherapy. Acta Oncologica 39: 383-388, 2000.

584.      Horsman, M.R., Chaplin, D.J., Christensen, K.L. & Overgaard, J.: Cadralazine: a less toxic but equally effective analogue of hydralazine in vivo. Experimental Oncology 22: 32-37, 2000.

585.      Horsman, M.R., Lindegaard, J.C., Grau, C., Nordsmark, M. & Overgaard, J.: Dose reponse modifiers in radiation therapy. In: Gundersson, L. & Tepper, J. (eds.) Clinical Radiation Oncology, Churchild Livingstone, London, pp. 155-168, 2000.

586.      Horsman, M.R., Murata, R., Breidahl, T., Nielsen, F.U., Maxwell, R.J., Stødkilde-Jørgensen, H. & Overgaard, J.: Combretastatins: novel vascular targeting drugs for improving anti-cancer therapy. Adv. Exp. Med. Biol. 476: 311-23, 2000.

587.      Højris, I., Andersen, J., Overgaard, M. & Overgaard, J.: Late treatment-related morbidity in breast cancer patients randomized to postmastectomy radiotherapy and systemic treatment versus systemic treatment alone. Acta Oncologica 39: 355-372, 2000.

588.      Højris, I., Rønnow Sand, N.P., Andersen, J., Rehling, M. & Overgaard, M.: Myocardial perfusion imaging in breast cancer patients treated with or without postmastectomy radiotherapy.  Radiotherapy and Oncology 55: 163-172, 2000.

589.      Johansen, J., Overgaard, J., Blichert-Toft, M. & Overgaard, M.: Treatment morbidity associated with the management of the axilla in breast-conserving therapy.  Acta Oncologica 39: 349-354, 2000.

590.      Johansen, L.V., Grau, C. & Overgaard, J.: Hypopharyngeal squamous cell carcinoma. Treatment results in 138 consecutively admitted patients. Acta Oncologica 39: 529-536, 2000.

591.      Johansen, L.V., Grau, C. & Overgaard, J.: Squamous cell carcinoma of the oropharynx. An analysis of treatment results in 289 consecutive patients. Acta Oncologica 39: 985-994, 2000.

592.      Kocak, Z. & Overgaard, J.: Risk factors of arm lymphedema in breast cancer patients. Acta Oncologica 39: 389-392, 2000.

593.      Lindegaard, J. & Grau, C.: Has the outlook improved for amifostine as a clinical radioprotector? Radiotherapy and Oncology 57: 113-118, 2000.

594.      Lundby, L., Overgaard, J. & Laurberg, S.: Histopathological and morphometric analyses of late rectal injury after irradiation. APMIS 108: 216-222, 2000.

595.      Overgaard, J.: A tribute to the founding editor (editorial). Radiotherapy and Oncology 55: 203-204, 2000.

596.      Overgaard, J. & Bartelink, H.: Breast cancer survival advantage with radiotherapy (letter). Lancet 356: 1269-1270, 2000. 

597.      Overgaard, J.: Management of the axilla in breast cancer. Implications for diagnosis, prognosis, treatment and morbidity (Editorial). Acta Oncologica 39: 259-260, 2000.

598.      Overgaard, J., Alsner, J., Eriksen, J., Horsman, M.R. & Grau, C.: Importance of overall treatment time for the response to radiotherapy in patients with squamous cell carcinoma of the head and neck. RAYS - Int. J. Radiol. Sciences 25: 313-319, 2000.

599.      Overgaard, J. Eriksen, J. & Alsner, J.: Repopulation kinetics in head and neck cancer require tissue and tumor cell interaction - a hypothesis. In: Moriarty, M. et al. (eds). Radiation Research. Vol. 2. Proceedings of the Eleventh International Congress of Radiation Research, Dublin, pp. 668-671, 2000.

600.      Overgaard, J., Yilmaz, M., Guldberg, P., Hansen, L.-L. & Alsner, J.: TP53 mutation is an independent prognostic marker for poor outcome in both node-negative and node-positive breast cancer. Acta Oncologica 39: 327-333, 2000.

601.      Nielsen, F.U.: Implementation and development of 1H and 13C nuclear magnetic resonance spectroscopy methods for studying tumour metabolism. Ph.D. thesis, Faculty of Health Sciences, University of Aarhus, 2000.

602.      Nordsmark, M. & Overgaard, J.: A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiotherapy and Oncology 57: 39-43, 2000.

603.      Nordsmark, M. & Overgaard, J.: Impossia tumorale. Patofisiologia, importanza clinica e prospettive terapeutiche. L’ossigenazione dei tumori umani: l’esperienza di Aarhus. Eds. Peter Vaupel, Debra Kelleher e Marina Ziche. Il pensiero scietifico editore. vol 3: pp 27-40,  2000.

604.      Nyvang, G.B., Mogensen, O., Bichel, P. & Jacobsen, A.:Combined prognostic importance of CA 125, histopathologic grade and DNA-index in advanced ovarian cancer. Eur. J. Gynaecol. Oncol. 21: 569-572, 2000.

605.      Ravnsbæk Jensen, A.. & Overgaard, J.: Ventetid i radioterapi; har det prognostisk betydning. Ugeskr. Læg. 161: 1357-1361, 2000.

606.      Safwat, A.: The immunobiology of low-dose total-body irradiation: more questions than answers. Radiat. Res. 153: 599-604, 2000.

607.      Safwat, A.: The role of low-dose total body irradiation in the treatment of non-Hodgkin’s lymphoma: A new look at an old method. Radiotherapy and Oncology 56: 1-8, 2000.

608.      Safwat, A., Bentzen, S.M., Nielsen, O.S. & Overgaard, J.: Time-course for the hazards of murine renal damage induced by total body irradiation. Int. J. Radiat. Biol.  76: 979-983, 2000.

609.      Siemann, D.W., Warrington, K.H. & Horsman, M.R.: Targeting tumor blood vessels: An adjuvant strategy for radiotherapy. Radiotherapy and Oncology 57: 5-12, 2000.

610.      Skoczylas, J.Z., Bentzen, S.M., Overgaard, M. & Overgaard, J.: Time course of radiological lung density changes after postmastectomy radiotherapy. Acta Oncologica 39: 181-187, 2000.

611.      Trans Fuglsang, J.: The role of TGF-$1 in development of radiation induced fibrosis. M.S. thesis, Faculty of Natural Sciences, University of Aarhus, 2000.