Department of Experimental Clinical Oncology

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187.      Andersen, J., Thorpe, S., Rose, C., Christensen, I., Rasmussen, B.B. & Poulsen, H.S.: Estrogen receptor in primary breast cancer estimated in paraffin embedded tissue. A study of its usefulness compared to dextran-coated charcoal assay. Acta Oncologica 30: 685-690, 1991.

188.      Becker, U., Andersen, J., Poulsen, H.S., Burcharth, F., Gluud, C. & Horn, T.: Enzyme immunoassay of oestrogen receptors in needle biosies from human liver. Liver 11: 292-299, 1991.

189.      Bentzen, S.M. & Grau, C.: Direct estimation of the fraction of hypoxic cells from tumor-control data obtained under aerobic and clamped conditions. Int. J. Radiat. Biol. 59: 1435-1440, 1991.

190.      Bentzen, S.M., Johansen, L.V., Overgaard, J. & Thames, H.D.: Clinical radiobiology of squamous cell carcinoma of the oropharynx. Int. J. Radiation Oncology Biol. Phys. 20: 1197-1206, 1991.

191.      Bentzen, S.M. & Overgaard, M.: Relationship between early and late normal-tissue injury after postmastectomy radiotherapy. Radiotherapy and Oncology 20: 159-165, 1991.

192.      Bentzen, S.M. & Thames, H.D.: Clinical evidence for tumor clonogen regeneration: interpretations of the data. Radiotherapy and Oncology 22: 161-166, 1991.

193.      Bichel, P. Jakobsen, A. & Ørntoft, T.F.: Histochemical distribution of CA-125 as a prognostic indicator in patients with serous ovarian cancer. Int. J. Gynecol. Cancer 1: 199-204, 1991.

194.      Brown, J.M., Lemmon, M.J., Horsman, M.R. and Lee, W.W.: Structure activity relationships for tumor radiosensitization by analogs of nicotinamide and benzamide. Int. J. Radiation Biol. 59: 739-748, 1991.

195.      Chaplin, D.J., Horsman, M.R. and Aoki, D.: Nicotinamide, Fluosol DA and Carbogen: A strategy to reoxygenate acutely and chronically hypoxic cells in vivo. Brit. J. Cancer 63: 109-13, 1991.

196.      Chaplin, D.J., Horsman, M.R., Peters, C.E. & Trotter, M.J.: Tumour blood flow and its modulation: Implications for bioreductive drug activity in vivo. In: Selective Activation of Drugs by Redox Processes. Nato ASI Series. G.E. Adams, A. Breccia, E.M. Fielden and P. Wardman, Eds., Plenum Press, New York pp. 325-336, 1991.

197.      Chaplin, D.J., Peters, C.E., Horsman, M.R. and Trotter, M.J.: Drug induced perturbations in tumour blood flow: therapeutic potential and possible limitations. Radiotherapy and Oncology 20: (suppl 1), 93-102, 1991.

198.      Fisker, R.V., Horsman, M.R. & Overgaard, J.: Hydralazine induced changes in tissue perfusion and radiation response in a C3H mammary carcinoma and mouse normal tissue. Acta Oncologica 30: 641-647, 1991.

199.      Grau, C. & Overgaard, J.: Radiosensitizing and cytotoxic properties of Mitomycin C in a C3H mammary carcinoma in vivo. Int. J. Radiation Oncology Biol. Phys. 20: 265-269, 1991.

200.      Grau, C., Møller, K., Overgaard, M., Overgaard. J. & Elbrønd. O.: Sensorineural hearing loss in patients treated with irradiation for nasopharyngeal carcinoma. Int. J. Radiation Oncology Biol. Phys. 21: 723-728, 1991.

201.      Hansen, P.V., Glavind, K., Panduro, J. & Pedersen, M.: Paternity in patients with testicular germ cell cancer: pretreatment and post-treatment findings. Eur. J. Cancer 27: 1385-1389, 1991.

202.      Hansen, P.V. & Sørensen, D.: Effect of vincristine or bleomycin on radiation induced cell kill of mice spermatogonial stem cells. Int. J. Radiation Oncology Biol. Phys. 20: 339-341, 1991.

203.      Horsman, M.R.: Nicotinamide and the hypoxia problem. Editorial. Radiotherapy and Oncology 22: 79-80, 1991.

204.      Horsman, M.R., Chaplin, D.J., Kristjansen, P.E.G. & Overgaard, J.: Tumour radiosensitization by nicotinamide. Eur. Cancer. News vol 4, no. 6, 1991.

205.      Horsman, M.R., Chaplin, D.J. & Overgaard, J.: The use of blood flow modifiers to improve the treatment response of solid tumours. Radiotherapy and Oncology 20: (suppl 1), 47-52, 1991.

206.      Horsman, M.R., Chaplin, D.J. & Overgaard, J.: The effect of combining Flavone Acedic Acid and hyperthermia on the growth of a C3H mammary carcinoma in vivo. Int. J. Radiat. Biol. 60: 385-388, 1991.

207.      Horsman, M.R., Christensen, K.L., Chaplin, D.J. & Overgaard, J.: Improved treatment of tumours in vivo by combining the bioreductive drug RSU-1069, hydralazine and hyperthermia. In: Selective Activation of Drugs by Redox Processes. Nato ASI Series. G.E. Adams, A. Breccia, E.M. Fielden and P. Wardman, Eds., Plenum Press, New York pp. 193-202, 1991.

208.      Jacobsen, A., Bichel, P. & Stornes, I.: Prognostic significance of DNA index in advanced ovarian cancer. Int. J. Cancer, 1: 195-97, 1991.

209.      Jakobsen, M., Høyer, M., Bentzen S.M. & Nielsen, K.: DNA flow cytometry in uterine endometrial carcinomas. APMIS Suppl. 23: 107-112, 1991.

210.      Jørgensen, K. & Hansen, O.: Strubehovedkræft. In: Lægevidenskab ved Odense Universitet. Siboni K (ed.). Odense Universitetsforlag, pp 213-228, 1991.

211.      Kamby, C., Andersen, J., Ejlertsen, B., Birkler, N.E., Rytter, L., Zedeler, K. & Rose, C.: Pattern of spread and progression in relation to the characteristiics of the primary tumour in human breast cancer. Acta Oncologica 30: 301-308, 1991.

212.      Langkilde, N.C., Wolf, H. Meldgaard, P., & Ørntoft, T.F.: Frequency and mechanism of Lewis antigen expression in human urinary bladder and colon carcinoma patients. Br. J. Cancer 63: 583-586, 1991.

213.      Langkilde, N.C., Wolf, H. & Ørntoft, T.F.: Lewis antigen expression in benign and malignant tissues from various organs in RBC (Le(a-b-) patients. Br. J. Haematol. 79: 493-499, 1991.

214.      Lee, F., McHugh, T.A., Solomon, M.H., Dorr, R.P., Siders, D.B., Kirscht, J.L.. Christensen, L.L. & Mitchell, A.: Transrectal ultrasound, digital rectal examination and prostate-specific antigen: preliminary results of an early detection program for prostate cancer. Scand. J. Urol. Nephrol.(Suppl) 137: 101-105, 1991.

215.      Leer, J.W.H., Overgaard, J. & Heeren, G.: The European core curriculum on training in radiotherapy. Radiotherapy and Oncology 22: 153-155, 1991.

216.      Lindegaard, J.C., Grau, C. & Overgaard, J.: Effect of step-down heating on hyperthermic radiosensitization and hyperthermic cytotoxicity in a C3H mammary carcinoma in vivo. Int. J. Radiat. Biol. 60: 707-721, 1991.

217.      Lindegaard, J.C. & Nielsen, O.S.: Sensitization to hyperthermia induced in a normal tissue by step-down heating. Int. J. Radiation Oncology, Biol. Phys. 20: 1023-1029, 1991.

218.      Lindegaard, J.C., Overgaard, J. & Nielsen, O.S.: A comparison of the effect of step-down heating in a tumour and a normal tissue in vivo. Int. J. Hyperthermia 7: 519-526, 1991.

219.      Lote, K., Møller, T., Nordman, E., Overgaard, J. & Sveinsson, Th.: Resources and productivity in radiation oncology in Denmark, Finland, Iceland, Norway and Sweden during 1987. Acta Oncologica 30: 555-561, 1991.

220.      Mandel, U., Ørntoft, T.F., Holmes, E., Clausen, H., Hakomori, S. & Dabelsteen, E.: Lewis blood group antigens in salivary glands and stratified epithelium: Lack of regulation of Lewis antigen expression in ductal and buccal mucosal lining epithelia. Vox Sanguinis 61: 205-214, 1991.

221.      Munro, A.J., Nielsen, O.S., Duncan, W., Sturgeon, J., Gospodarowics, M.K., Malkin, A., Thomas, G.M. & Jewett, M.A.S.: An assessment of combined tumour markers in patients with seminoma: placental alkaline phosphatase (PLAP), lactate dehydrogenase (LD) and beta human chorionic gonadotropin (beta-HCG). Br. J. Cancer. 64: 537-542, 1991.

222.      Nielsen, O.S., Cummings, B., O'Sullivan, B., Catton, C., Bell, R.S. & Fornasier, V.L.: Preoperative and postoperative irradiation of soft tissue sarcomas: effect on radiation field size. Int. J. Radiation Oncol. Biol. Phys. 21: 1515-1518, 1991.

223.      Nielsen, O.S., Munro, A.J. & Tannock, I.F.: Management policy for treatment of bone metastases. J. Clin. Oncol. 9: 509-524, 1991.

224.      Overgaard, J.: Taking advantage of tumour hypoxia - a concensus. Radiotherapy and Oncology 20: (suppl 1), 117, 1991.

225.      Overgaard, J., Grau, C., Lindegaard, J.C. & Horsman, M.R.: The potential of using hyperthermia to eliminate radioresistant hypoxic cells. Radiotherapy and Oncology 20: (suppl 1), 113-116, 1991.

226.      Overgaard, J., Radacic, M. & Grau, C.: Interaction of hyperthermia and cis-diamminedichloroplatinum(II) alone or combined with radiation in a C3H mammary carcinoma in vivo. Cancer Res. 51: 707-711, 1991.

227.      Overgaard, J., Sand Hansen, H., Lindeløv, B. Overgaard, M., Jørgensen, K., Rasmusson, B. & Berthelsen, A.: Nimorazole as a hypoxic radiosensitizer in the treatment of supraglottic larynx and pharynx carcinoma. First report from the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85. Radiotherapy and Oncology 20: (suppl 1), 143-150, 1991.

228.      Petersen, S.E., Madsen, A.L. & Bak, M.: Chromosome number distribution and cellular DNA content in colorectal adenomas from polyposis and non-polyposis patients. Cancer Genet. Cytogenet. 53: 219-228, 1991.

229.      Stewart, F.A., Lundbeck, F., Oussoren, Y. & Luts, A.: Acute and late radiation damage in mouse bladder. A comparison of urination frequency and cystometry. Int. J. Radiation Oncology Biol. Phys. 21: 1211-1219, 1991.

230.      Sørensen, F.B., Kristensen, I.B., Grymer, F. & Jacobsen, A.: DNA level, tumour thickness and stereological estimates of nuclear volume in stage I cutaneous malignant melanomas. Am. J. Dermatopathol. 13: 11-19, 1991.

231.      Wood, P.J., Counsell, C.J.R., Bremner, J.C.M., Horsman, M.R. & Adams, G.E.: The measurement of radiosensitizer induced changes in mouse tumour metabolism by 31-P magnetic resonance spectroscopy. Int. J. Radiat. Oncol. Biol. Phys. 20: 291-294, 1991.

232.      Ørntoft, T.F., Greenwell, B., Clausen, H. & Watkins, W.M.: Regulation of the oncodevelopmental expression of type 1 chain ABH and Lewisb blood group antigens in human colon by alpha-2-L-fucosylation. Gut 32: 287-293, 1991.

233.      Ørntoft, T.F., Holmes, E., Johnson, P., Hakomori, S. & Clausen, H.: Differential tissue expression of the lewis blood group antigens: enzymatic, immunohistologic and immunochemical evidence for lewis a and b antigen expression in Le(A-B-) individuals. Blood 77: 1389-1396, 1991.

234.      Ørntoft, T.F., Langkilde, N.C., Wiener, H. & Ottosen, P.: Cellular localization of PNA-binding in colorectal andenomas: Comparison to with differentiation, nucleus: cell height ration and effect of desialylation. APMIS 99: 275-281, 1991.