Department of Experimental Clinical Oncology

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81. Andersen, J. Poulsen, H.S.: Immunohistochemical estrogen receptor determination in paraffin-embedded tissue - prediction of response to hormonal treatment in advanced breast cancer. Cancer 64: 1901-1908, 1989.

82. Andersen, J.: Skovbon, H. Poulsen, H.S.: Immunocytochemical determination of the estrogen regulated protein Mr 24,000 in primary breast cancer and response to endocrine therapy. Eur. J. Cancer Clin. Oncol. 25: 641-643, 1989.

83. Balslev, I., Pedersen, M., Teglbjærg, P.S., Hanberg-Sørensen, F., Bone, J., Jacobsen, N.O., Overgaard, J., Sell, A., Bertelsen, K., Fenger, C., Hage, E., Kronborg, O., Hansen, L., Høstrup, H. & Nørgaard-Pedersen, B.: Prognosen ved synkrone levermetastaser fra kolorectal cancer. Ugeskr. læg. 151: 1045-1048, 1989. 

84. Bentzen, S.M., Overgaard, J., Thames, H. D., Overgaard, M., Hansen, P. V., von der Maase, H. Meder, J.: Clinical radiobiology of malignant melanoma. Radiotherapy and Oncology 16: 169-182, 1989.

85. Bentzen, S.M., Overgaard, M. Thames, H.D.: Fractionation sensitivity of a functional endpoint: impaired shoulder movement after post-mastectomy radiotherapy. Int. J. Radiation Oncology Biol. Phys. 17: 531-537, 1989.

86. Bentzen, S.M., Overgaard, M., Thames, H.D., Juul Christensen, J. Overgaard, J.. Early and late normal tissue injury after postmastectomy radiotherapy alone or combined with chemotherapy. Int. J. Rad. Biol. 56: 711-715, 1989.

87. Bentzen, S.M. Thames, H.: Are the results of the St. Thomas trial of post-mastectomy radiotherapy inconsistent with the predictions from the linear-quadratic model? (Letter to the editor). Brit. J. Radiology 62: 633-635, 1989.

88. Bentzen, S.M. Thames, H.: Is there an influence of overall treatment time in the response of lung to fractionated radiotherapy. Radiotherapy and Oncology 14: 171-173, 1989.

89. Bentzen, S.M. Thames, H.: Incidence and latency of radiation reactions. (Letter to the editor). Radiotherapy and Oncology 14: 261-263, 1989.

90. Bentzen, S.M., Thames, H. Overgaard, M.: Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study. Radiotherapy and Oncology 15: 267-274, 1989.

91. Bentzen, S.M., Thames, H.D., Travis, E.L., Ang, K.K., v.d. Schueren, E., Dewit, L. Dixon, D.O.: Direct estimation of latent time for radiation injury in late-responding normal tissues: gut, lung and spinal cord. Int. J. Radiat. Biol. 55: 27-43, 1989.

92. Chaplin, D.J., Acker, B.D. Horsman, M.R.: Reduction of tumour blood flow by vasoactive drugs: a role in cancer therapy. Biomedica Biochemica Acta 48: S264-S268, 1989.

93. Chaplin, D.J., Horsman, M.R. Overgaard, J.: The in vivo tumour interaction between nitroaromatic compounds, hydralazine and hyperthermia. In: Hyperthermic Oncology 1988, Vol. 1. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 272-273, 1989.

94. Hansen, P.V., Trykker, H., Andersen, J. & Helkjær, P.E.: Germ cell function and hormonal status in patients with testicular cancer. Cancer 64: 956-961, 1989.

95. Hansen, P.V., Trykker, H., J. Helkjær, P.E. Andersen, J.: Testicular function in patients with testicular cancer on surveillance and after chemotherapy. J. Nat. Cancer Inst. 81: 1246-1250, 1989.

96. Horsman, M.R., Chaplin, D.J., and Brown, J.M. Tumor radiosensitization by nicotinamide: a result of improved blood flow and oxygenation. Radiat. Res. 118: 139-150, 1989.

97. Horsman, M.R., Christensen, K.L. Overgaard, J.: Hydralazine induced enhancement of hyperthermic damage in the C3H mammary carcinoma. Int. J. Hyperthermia 5: 123-136, 1989.

98. Horsman, M.R., Gyldenhof, B. Overgaard, J.: Effect of local hyperthermia on the vascularity of a C3H mammary carcinoma and its surrounding skin. In: Hyperthermic Oncology 1988, Vol. 1. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 342-343, 1989.

99. Horsman, M. R., Hansen, P. V. Overgaard, J.: Radiosensitization by nicotinamide in tumor and normal tissues: the importance of tissue oxygenation status. Int. J. Radiation Oncol. Biol. Phys. 16: 1273-1276, 1989.

100. Horsman, M.R. Overgaard, J.: Thermal radiosensitization in animal tumors: the potential for therapeutic gain. In: Hyperthermia and Oncology, Vol 2. (eds.: Urano, M. Douple, E.) VNU Scientific Publishers, The Netherlands, pp. 113-145, 1989. 

101. Horsman, M.R. Overgaard, J.: The enhancement of hyperthermic damage in tumours and normal tissues by hydralazine. In: Hyperthermic Oncology 1988, Vol. 1. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 270-271, 1989.

102. Horsman, M.R., Overgaard, J., Christensen, K.L., Trotter, M.J. and Chaplin, D.J.: Mechanism for the reduction of tumour hypoxia by nicotinamide and the clinical relevance for radiotherapy. Biomedica Biochemica Acta 48: S251-S254, 1989.

103. Horsman, M.R. and Winther, J.: Vascular effects of photodynamic therapy in an intraocular retinoblastoma-like tumour. Acta Oncologica 28: 693-697, 1989.

104. Horsman, M.R., Wood, P.J. and Brown, J.M. Misonidazole chemosensitization of EMT6 spheroids to melphalan. Radiotherapy and Oncology 15: 103-114, 1989.

105. Hug, V., Thames, H.D. Bentzen, S.M.: Predictors of hormone response for patients with ER-unknown breast tumours. Brit. J. Cancer 59: 421-425, 1989.

106. Kamby, C., Ejlertsen, B., Andersen, J., Birkler, N.E., Rytter, L., Zedeler, K. Rose, C. Body size and menopausal status in recurrent breast cancer. Acta Oncologica 28: 795-799, 1989.

107. Kano, E. Nielsen, O.S.: Modification of thermotolerance. In: Hyperthermic Oncology 1988, Vol. 2. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 221-222, 1989.

108. Langkilde, N.C., Hastrup, J., Olsen, S., Wolf, H. Ørntoft, T.F.: Immunohistochemistry and cytochemistry of experimental rat bladder cancer: Binding of lectins PNA and WGA, and of a Ley mouse monoclonal antibody. J. Urol. 141: 981-986, 1989.

109. Langkilde, N.C., Wolf,H. Ørntoft,T.F.: Lectino-histochemistry of human bladder cancer: Loss of lectin binding structures in invasive carcinomas. APMIS 97: 367-373, 1989.

110. Langkilde N.C., Wolf, H. Ørntoft,T.F.: Binding of WGA and PNA lectins to human transitional cell carcinomas: Correlation with histopathologic grade, invasion and DNA-ploidy. Cancer 64: 848-853, 1989.

111. Langkilde, N.C., Wolf, H. Ørntoft, T.F.: DNA replication in experimental rat bladder tumors: immunohistochemical detection of Bromodeoxyuridine labelled nuclei. Scan. J. Urol. Nephrol. Suppl. 125: 133-139, 1989.

112. Lindegaard, J.C. Nielsen, O.S.: Thermotolerance in the mouse foot estimated at various levels of normal tissue damage. Int. J. Radiation Oncology Biol. Phys. 16: 1543-1549, 1989.

113. Lindegaard, J.C. O.S. Nielsen: Time-temperature relationships for step-down heated L1A2 cells in vitro. In: Hyperthermic Oncology 1988, Vol. 1. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 36-37, 1989.

114. Lindegaard, J.C. Overgaard, J.: The effect of step-down heating on the therapeutic ratio in X-irradiated experimental tumors. In: Hyperthermic Oncology 1988, Vol. 2. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 146-149, 1989.

115. Lundbeck, F., Djurhuus, J.C. & Vaeth, M.: Bladder filling in mice: an experimental in vivo model to evaluate the reservoir function of the urinary bladder in a long-term study. J. Urol. 141: 1245-1249, 1989.

116. Lundbeck, F., Jacobsen, F. Vaeth, M.: Impact of the category of early tumor recurrence on tumor progression in bladder tumors treated by transurethral resection. European Urology 16: 291-294, 1989.

117. Lundbeck, F., Ulsø, N. Overgaard, J.: Cystometric evaluation of early and late irradiation damage to the mouse urinary bladder. Radiotherapy and Oncology 15: 383-392, 1989.

118. Lundbeck, F. Stewart, F.: Acute changes in the bladder reservoir function after irradiation alone or in combination with chemotherapy: a matter of mouse strain. Scand. J. Urol. Nephrol. Suppl. 125: 141-148, 1989.

119. Momsen, S., Jakobsen, A. Sell, A.: Quality of life in patients with advanced bladder cancer. A randomized study comparing cystectomy and irradiation - the danish bladder cancer stydy group (DAVECA protocol 8201). Scand. J. Urol. Nephrol. Suppl. 125: 115-120, 1989.

120. Nielsen, K., Petersen, S.E. Ørntoft, T.. A comparison between stereological estimates of mean nuclear volume and DNA flow cytometry in bladder tumours. APMIS 97: 949-956, 1989.

121. Nielsen, K., Ørntoft, T.F., Petersen, S.E.: Stereological estimates of mean nuclear volume in bladder tumours: association with heterogeneic expression of blood group antigens and with DNA flowcytometry. Acta Stereologica 8: 355-360, 1989.

122. Nielsen, K., Ørntoft, T.F., and Wolf, H.: Stereological estimates of nuclear volume in non-invasive bladder tumors (Ta) correlated with the recurrence pattern. Cancer 64: 2269-2274, 1989.

123. Nielsen, O.S.: Current overview of thermotolerance and its modification. In: Hyperthermic Oncology 1988, Vol. 2. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 235-237, 1989.

124. Nielsen, O.S.: Are thermotolerance kinetics different for heat combined with radiotherapy ?. In: Hyperthermic Oncology 1988, Vol. 2. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 217-218, 1989.

125. Nielsen, O.S. Poulsen, H.S.: Knoglemetastaser. Ugeskr. Læg. 151: 362-365, 1989.

126. Overgaard, J.: The current and potential role of hyperthermia in radiotherapy. Int. J. Radiation Oncol. Biol. Phys. 16: 535-549, 1989.

127. Overgaard, J.: Hyperthermia in tumor treatment. In: Cancer therapy: new trends. Bannasch. P. (ed). Springer Verlag, Berlin pp. 61-70, 1989.

128. Overgaard, J.: Clinical trials with hyperthermia and radiotherapy. In: Hyperthermic Oncology 1988, Vol. 2. Sugahara, T. Saito, M. (eds). Taylor and Francis, London Philadelphia, pp. 57-62, 1989.

129. Overgaard, J.: Combined hyperthermia and radiation treatment of malignant melanoma. In: Hyperthermic Oncology 1988, Vol. 2. Sugahara, T. Saito, M. (eds). Taylor and Francis, London & Philadelphia, pp. 464-467, 1989.

130. Overgaard, J.: Sensitization of hypoxic tumour cells - clinical experience. Int. J. Rad. Biol. 56: 801-811, 1989.

131. Overgaard, J., Bentzen, S. M., Kolstad, P., Kjoerstad, K., Davy, M., Bertelsen, K., Mäntyla, M., Frankendal, B., Skryten, A., Löftquist, I., Pedersen, M., Sell, A. Jensen, R. H..: Misonidazole combined with radiotherapy in the treatment of carcinoma of the uterine cervix. Final report from the Scandinavian multicenter study. Int. J. Radiation Oncol. Biol. Phys. 16: 1069-1072, 1989.

132. Overgaard, J., Sand Hansen, H., Andersen, A.P., Hjelm-Hansen, M., Jørgensen, K., Sandberg, E., Berthelsen, A., Jensen, R.H. Pedersen, M.: Misonidazole combined with split-course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx. Final report from the DAHANCA 2 study. Int. J. Radiation Oncol. Biol. Phys. 16: 1065-1068, 1989.

133. Poulsen, H.S., Nielsen, O.S., Klee, M. Rørth, M.: Palliative irradiation of bone metastasis: A review. Cancer Treatment Review 16: 41-48, 1989.

134. Radacic, M., Grau, C., Horsman, M.R. Overgaard, J.: Interaction between hyperthermia, cis-diamminedichloroplatinum and radiation in a C3H mouse mammary carcinoma in vivo. Iugoslav. Physiol. Pharmacol. Acta 24 (suppl 6): 367-368, 1989.

135. Scopsi, L., Balslev, E., Andersen, J., Brünner, N., Poulsen, H.S. Larsson, L.I.: Immunoreactive opioid peptides in human breast cancers. American J. Pathology 134: 473-479, 1989.

136. Thames, H.D., Bentzen, S.M., Turesson, I, Overgaard, M. van der Bogaert, W.: Fractionation parameters for human tissues and tumors. Int. J. Rad. Biol. 56: 701-710, 1989.

137. Thames, H.D., Mason, K.A., Bentzen, S.M., Ang, K.K. Cundiff, J.: Split-dose recovery in mouse jejunal crypt cells: characterization of repair kinetics. In: McNally, N.J. (ed.) The Scientific Basis of modern Radiotherapy. British Institute of Radiology Report No. 19, 37-42, 1989.

138. Winther, J.:  Effect of Photofrin II and light energy on retinoblastoma-like cells in vitro - dose-response relationships, light dose rate effect and recovery ratio. J. Cancer Res. Clin. Oncol.: 115: 73-78, 1989.

139. Winther, J.: Cell survival in an intraocular retinoblastoma-like tumour assessed 30 min. to 48 hours after photodynamic therapy by an in vivo-in vitro clonogenic assay. Brit. J. Cancer 59: 869-872, 1989.

140. Winther, J Overgaard, J.: Dose-response relationship of photodynamic therapy in an intraocular retinoblastoma like tumour and on normal eye tissues. Acta Ophtalmologica 67: 44-50, 1989.

141. Ørntoft, T.F., Hvid, H., Clausen, H., Hakomori, S. Dabelsteen, E.: Loss of blood group ABO-antigen expression in urothelium from patients with chronic cystitis. Lab Invest. 60: 305-310, 1989.

142. Ørntoft, T.F. Nielsen, K.: Heterogeneity of blood group A and H isoantigens in bladder tumours: association with nuclear volume. J. Histochem. Cytochem. 37: 1153-1155, 1989.

143. Ørntoft, T.F., Wolf, H., Clausen, H., Dabelsteen, E. Hakomori, S.: Blood group ABH-related antigens in normal and malignant bladder urothelium: possible structure basis for the deletion of type 2 chain ABH antigens in invasive carcinomas. Int. J. Cancer 43: 774-780, 1989.