Department of Experimental Clinical Oncology

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34. Andersen, J., Bentzen, S.M.; Poulsen, H.S: Relationship between radioligand binding assay, immunoenzyme assay and immunohistochemical assay for estrogen receptors in human breast cancer and association with tumor differentiation. Europ. J. Cancer Clin. Oncol. 24: 377-384, 1988.

35. Andersen, J.; Poulsen, H.S.: Immunohistochemical analysis of estrogen receptors using formalin-fixed paraffin embedded breast cancer tissue: Correlation with clinical endocrine response. J. steroid. Biochem. 30: 337-339, 1988.

36. Andersen, J. ; Poulsen, H.S.: Relationship between estrogen receptor status in the primary tumor and its regional and distant metastases - an immunohistochemical study in human breast cancer. Acta Oncologica 27: 761-766, 1988.

37. Andersen, J., Ørntoft, T.F. ; Poulsen, H.S.: An immunohistochemical method for demonstrating estrogen receptors in formalin fixed paraffin embedded human breast cancer tissue using a monoclonal antibody to estrophilin. J Histochem. Cytochem. 36: 1553-1560, 1988.

38. Arcangeli, G., Overgaard, J., Gonzalez Gonzalez, D. ; Shrivastava, P.N.: Hyperthermia trials. Int. J. Radiation Oncology Phys. Biol. 14: S93-S109, 1988.

39. Arheden, K., Tommerup N., Mandahl N., Heim S., Winther J., Jensen O. A., Prause J. ; Mitelman F.: Amplification of the human putative oncogene INT1 in primary retinoblastoma tumors. Cytogenet. Cell Genet. 48: 174-177, 1988.

40. Balslev, I., Pedersen, M., Teglbjærg, P.S., Hanberg-Sørensen, F., Bone, J., Jacobsen, N.O., Overgaard, J., Sell, A., Bertelsen, K., Fenger, C., Hage, E., Kronborg, O., Hansen, L., Høstrup, H. ; Nørgaard-Pedersen, B.: Postoperativ stråleterapi ved cancer recti et sigmoidei. En prospektiv, randomiseret multicenterundersøgelse. Ugeskr. læg. 150: 1958-1961, 1988.

41. Bentzen, S.M., Balslev, I., Pedersen, M., Teglbjærg, P.S., Hanberg-Sørensen, F., Bone, J., Jacobsen, N.O., Overgaard, J., Sell, A., Bertelsen, K., Hage, E., Fenger, C., Kronborg, O., Hansen, L., Høstrup, H. ; NørgaardPedersen, B.: A regression analysis of prognostic factors after resection of Dukes' B and C carcinoma of the rectum and rectosigmoid. Does postoperative radiotherapy change the prognosis? Brit. J. Cancer 58: 195-201, 1988.

42. Bentzen, S.M., Juul Christensen, J., Overgaard, M. ; Overgaard, J.: Some methodological problems in estimating radiobiological parameters from clinical data. Alpha/beta ratios and electron RBE for cutaneous reactions in patients treated with post-mastectomy radiotherapy. Acta Oncologica 27: 105-116, 1988.

43. Bentzen, S.M., Poulsen, H.S., Kaae, S., Myhre Jensen, O., Johansen, H., Mouridsen, H.T., Daugaard, S. ; Arnoldi, C.: Prognostic factors in osteosarcomas. A regression analysis. Cancer 62: 194-202, 1988.

44. Bukh, A., Aguado, M.T., Krarup, N., Poulsen, H.S., Nordentoft, A.M. ; Møller, N.P.H.: Breast cancer: A prospective evaluation of circulating immune complex levels during the first year after mastectomy. Int. J. Cancer 41: 364-370, 1988.

45. Chaplin, D.J. ; Horsman, M.R.: The effect of artificially induced hyperglycemia on the radiation response of the Lewis lung and EMT6 tumor models. Int. J. Radiat. Biol. 54: 803-811, 1988.

46. Frost, P., Harving, N., Langkilde, N.C. Wolf, H., Bendtsen, L., Ørntoft, T.F.: Wheat Germ Agglutinin (WGA): A new marker of cellular atypia in human bladder tumors. Lectins, Biology, Biochemistry, Clinical Biochemistry, 6:615-618, 1988.

47. Grau, C. ; Overgaard, J.: Effect on cancer chemotherapy on the hypoxic fraction in a solid tumor measured using a local tumor control assay. Radiotherapy and Oncology 13: 301-309, 1988.

48. Horsman, M.R., Brown, J.M., Hirst, V.K., Lemmon. M.J., Wood, P.J., Dunphy, A.P. ; Overgaard, J.: Mechanism of action of the selective tumor radiosensitizer nicotinamide. Int. J. Radiation Oncol. Biol. Phys. 15: 685-690, 1988.

49. Horsman, M. R., Overgaard, J. ; Chaplin, D. J.: The interaction between RSU-1069, hydralazine and hyperthermia in a C3H mammary carcinoma as assessed by tumor growth delay. Acta Oncologica 27: 861-862, 1988.

50. Jacobsen, A., Bichel, P., Kristensen, G.B. ; Nyland, M.: Prognostic influence of ploidy level and histopathological differentiation in cervical carcinoma stage Ib. Eur. J. Cancer Clin. Oncol. 24: 969-972, 1988.

51. Jacobsen, A., Hansen, V. ; Poulsen, H.S.: DNA profile and steroid receptor content of human ovarian cancer. Eur. J. Gynaecol. Oncol. 9: 461-463, 1988.

52. Kamby, C., Andersen, J., Ejlertsen, B., Birkler, N.E., Rytter, L., Zedeler, K., Thorpe, S.M. ; Rose, C.: Histological grade and steroid receptor content of primary breast cancer - impact on prognosis and possible modes of action. Brit. J. Cancer. 58: 480-86, 1988.

53. Kamby, C., Ejlertsen, B., Andersen, J., Birkler, N.E., Rytter, L., Zedeler, K. ; Rose, C.: The pattern of metastases in human breast cancer - Influence of systemic adjuvant therapy and impact on survival. Acta Oncologica 27: 715-720, 1988.

54. Kamby, C., Rose, C., Eilertsen, B., Andersen, J., Birkler N.E., Rytter L., Andersen, K.W. ; Zedeler, K. Systemic adjuvant treatment and the pattern of recurrences in patients with breast cancer. Europ J Cancer Clin Oncol. 24: 439-447, 1988.

55. Kronborg, O., Fenger, C., Bertelsen, K., Hansen, L., Balslev, I., Pedersen, M., Teglbjærg, P.S., Hanberg-Sørensen, F., Bone, J., Jacobsen, N.O., Overgaard, J., Sell, A., Høstrup, H. ; Nørgaard-Pedersen, B.: Escape clauses in a multicenter trial. Unforeseen problems and their potential influence on the general validity of the conclusions. J. Theoretical Surgery 2: 157-166, 1988.

56. Langkilde, N.C., Harving, N., Nørgaard, P., Hastrup, J., Olsen, S., Wolf, H, Ørntoft, T.F.: An immunohistological and immunocytological study of PNA and WGA binding in N-nitroso-N-methyl-urea induced rat bladder cancer. Lectins, Biology, Biochemistry, Clinical Biochemistry 6: 619-624, 1988.

57. Lundbeck, F., Bruun, E., Finnerup, B. ; Strøyer Christophersen, I.: Intravesical therapy of non-invasive bladder tumors (stage Ta) with adriamycin: initial treatment results and the long term course. J. Urol. 139: 1212-1214, 1988.

58. Lindegaard, J.C. ; Overgaard, J.: Interaction of step-down heating on hyperthermic radiosensitization in an experimental tumor and a normal tissue in vivo. Radiotherapy and Oncology 11: 143-151, 1988.

59. Melgaard, B., Køhler, O., Sand Hansen, H., Overgaard, J., Munch-Hansen, J., ; Paulson, O.B.: Misonidazole neuropathy. A prospective study. J. Neuro-Oncology 6: 227-230, 1988.

60. Nielsen, O.S., von der Maase, H. ; Overgaard, J.: Combined effect of 5-fluoruracil and radiation on murine hematopoietic tissue. Radiotherapy and Oncology 13: 145-152, 1988.

61. Overgaard, J.: The influence of hemoglobin concentration on the response to radiotherapy. Scand. J. Clin. Lab. Invest. 48, Suppl. 189: 49-53, 1988.

62. Overgaard, J. (ed): Fractionation in Radiotherapy. Almqvist and Wiksell, Uppsala, 1988.

63. Overgaard, J.: The role of hyperthermia in radiotherapy. In: Kärcher, K.H. et al. (eds.): Progress in Radio-Oncology IV. ICRO, Vienna, pp. 247-251, 1988.

64. Overgaard, J. ; Overgaard, M.: Is there a role for hyperthermia in gastrointestinal tract cancer. Recent results in Cancer Research 110: 244-253, 1988.

65. Overgaard, J., Vendelbo Johansen, L., Hjelm-Hansen, M. ; Andersen, A.P.: Comparison of conventional and split-course radiotherapy as primary treatment in carcinoma of the larynx. Acta Oncologica 27: 147-152, 1988.

66. Overgaard, M.: Radiation-induced spontaneous ribfractures in breast cancer patients treated with postmastectomy irradiation. A clinical radiobiological analysis of fraction size and dose response relationships of late bone damage. Acta Oncologica 27: 117-122, 1988.

67. Overgaard, M., Christensen, J. J., Johansen, H., Nybo-Rasmussen, A., Frederiksen, P., Laursen, F., Brincher, H., van der Kooy, P., Gadeberg, C. C., Hjelm-Hansen, M., Panduro, J., Sørensen, N. E., Overgaard, J., West Andersen, K. ; Zedeler, K.: Postmastectomy irradiation in high risk breast cancer patients: present status of the Danish breast cancer cooperative group trials. Acta Oncologica 27: 707-714, 1988.

68. Petersen, S.E., Harving, N., Ørntoft, T. ; Wolf, H.: Conal heterogeneity of anneuploid cell populations in carcinoma in situ of the bladder: a flowcytometric study. Scand. J. Urol. Nephrol. 22, Suppl. 100: 213-217, 1988.

69. Poulsen, H.S.: In vitro observations in relation to response. In: Stoll, B.A. (ed): Endocrine management of Cancer, vol 1, Karger, Basel, pp. 72-83, 1988.

70. Thorpe, S.M., Poulsen, H.S., Pedersen, K.O. ; Rose, C.: Impact of standardization of estrogen and progesterone receptor assays of breast cancer biopsies in Denmark. Eur. J. Clin. Oncol.: 24: 1263-1269, 1988.

71. Thorpe, S.M., Poulsen, H.S., Pedersen, K.O. ; Rose, C.: Quality control of receptor analyses of breast cancer tissue in Denmark. Acta Oncologica 27: 621-626, 1988.

72. Vendelbo Johansen, L., Overgaard, J. ; Elbrønd, O.: Pharyngo-cutaneous fistulae following laryngectomy. Evaluation of radiotherapy and prophylactic metronidazole. Cancer 61: 673-678, 1988.

73. Winther, J. ; Ehlers, N.: Histopathological changes in an intraocular retinonblastoma-like tumour following photodynamic therapy. Acta Ophthalmologica 66, 69-78, 1988.

74. Winther, J., Ehlers, N., Jensen. O.A., Overgaard, J. ; Prause, J.U.: Predective value of flowcytometric DNAanalysis on fresh retinoblastoma tissue. Acta Ophthalmogica 66: 217-219, 1988.

75. Winther, J. Olsen, J.H. ; de Nully Brown, P.: Risk of non-occular cancer among retinoblastoma patients and their parents - a population-based study in Denmark, 1943-1984. Cancer 68: 1458-1462, 1988.

76. Winther, J., Overgaard, J. ; Ehlers, N.: Photodynamic therapy in management of an intraocular retinoblastoma like tumour assessed in situ and by in vivo-in vitro assay . Photochem. Photobiol. 47: 419-423, 1988.

77. Ørntoft, T.F., Petersen, S.E., Wolf, H.: Dual-parameter flow cytometry of transitional cell carcinomas: Quantitation of DNA content and binding of carbohydrate ligands in cellular subpopulations. Cancer 61: 963-970, 1988.

78. Ørntoft, T.F. and Wolf, H.: Blood group ABO and Lewis antigens in bladder tumours: Correlation between glycosyltransferase activity and antigen expression. APMIS 96: suppl. 4, 126-133, 1988.

79. Ørntoft, T.F., Wolf, H., Clausen, H., Hakomori, S. and Dabelsteen, E.: Blood group ABO-related antigens in fetal and normal adult bladder urothelium. Immunohistochemical study of Type 2 chain structures with a panel of mouse monoclonal antibodies. Lab. Invest 58: 576-583, 1988.

80. Ørntoft, T.F., Wolf, H. ; Watkins, W.M.: Activity of the human blood group ABO, Se, H, Le, and X gene-encoded glycosyltransferases in normal and malignant bladder urothelium. Cancer Res. 48: 4427-4433, 1988.